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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HES3
All Species:
3.64
Human Site:
S71
Identified Species:
8
UniProt:
Q5TGS1
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TGS1
NP_001019769.1
186
19968
S71
E
Q
P
S
G
F
R
S
C
L
P
G
V
S
Q
Chimpanzee
Pan troglodytes
XP_001162588
239
25232
E75
K
Y
R
A
G
F
S
E
C
M
N
E
V
T
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546749
200
21060
G86
Q
G
L
W
P
V
P
G
G
V
E
F
P
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61657
175
19275
S61
Q
G
L
W
P
V
P
S
G
V
D
Y
P
S
G
Rat
Rattus norvegicus
Q04667
175
19118
S61
Q
G
L
W
L
V
P
S
G
V
D
Y
P
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511924
287
29320
E98
K
Y
R
A
G
F
S
E
C
M
N
E
V
T
R
Chicken
Gallus gallus
O57337
290
31053
G114
V
L
G
K
Y
R
A
G
F
N
E
C
M
N
E
Frog
Xenopus laevis
Q8AVU4
267
28644
E116
K
Y
R
A
G
F
S
E
C
M
N
E
V
T
R
Zebra Danio
Brachydanio rerio
Q9I9L0
324
34311
G125
A
M
D
F
L
S
I
G
F
R
E
C
L
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26263
435
46532
G119
V
V
Q
K
F
K
T
G
F
V
E
C
A
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175739
383
41428
T210
A
N
K
T
P
F
M
T
S
L
Q
P
P
D
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28
N.A.
67
N.A.
65.5
63.9
N.A.
25.7
24.1
25.8
22.5
N.A.
20.9
N.A.
N.A.
21.9
Protein Similarity:
100
39.7
N.A.
70
N.A.
70.4
72
N.A.
35.8
36.2
35.9
33.3
N.A.
29.6
N.A.
N.A.
31.3
P-Site Identity:
100
26.6
N.A.
6.6
N.A.
13.3
13.3
N.A.
26.6
0
26.6
0
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
60
N.A.
20
N.A.
26.6
26.6
N.A.
60
20
60
20
N.A.
13.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
28
0
0
10
0
0
0
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
37
0
0
28
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
19
0
0
10
0
% D
% Glu:
10
0
0
0
0
0
0
28
0
0
37
28
0
10
28
% E
% Phe:
0
0
0
10
10
46
0
0
28
0
0
10
0
0
0
% F
% Gly:
0
28
10
0
37
0
0
37
28
0
0
10
0
0
28
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
28
0
10
19
0
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
28
0
19
0
0
0
0
19
0
0
10
0
0
% L
% Met:
0
10
0
0
0
0
10
0
0
28
0
0
10
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
10
28
0
0
10
0
% N
% Pro:
0
0
10
0
28
0
28
0
0
0
10
10
37
0
0
% P
% Gln:
28
10
10
0
0
0
0
0
0
0
10
0
0
0
10
% Q
% Arg:
0
0
28
0
0
10
10
0
0
10
0
0
0
0
28
% R
% Ser:
0
0
0
10
0
10
28
28
10
0
0
0
0
37
0
% S
% Thr:
0
0
0
10
0
0
10
10
0
0
0
0
0
37
0
% T
% Val:
19
10
0
0
0
28
0
0
0
37
0
0
37
0
0
% V
% Trp:
0
0
0
28
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
28
0
0
10
0
0
0
0
0
0
19
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _